Engineering biology is the set of methods for designing, building, and testing engineered biological systems which have been used to manipulate information, construct materials, process chemicals, produce energy, provide food, and help maintain or enhance human health and environment.[1]
History
Rapid advances in the ability to genetically modify biological organisms have advanced a new engineering discipline, commonly referred to as synthetic biology. This approach seeks to harness the power of living systems for a variety of manufacturing applications, such as advanced therapeutics, sustainable fuels, chemical feedstocks, and advanced materials. To date, research in synthetic biology has typically relied on trial-and-error approaches, which are costly, laborious, and inefficient.[2] Engineering biology methods include a combination of traditional biological techniques such as bioinformatics, molecular biology, and wet cell biology, as well as conventional engineering practices such as design and computation.[3]
References
- ^Endy, D. (2005). Foundations for engineering biology. Nature, 438(7067), 449-453. doi:10.1038/nature04342
- ^Hutchison, C. A., Chuang, R. Y., Noskov, V. N., Assad-Garcia, N., Deerinck, T. J., Ellisman, M. H., ... & Pelletier, J. F. (2016). Design and synthesis of a minimal bacterial genome. Science, 351(6280), aad6253. doi:10.1126/science.aad6253
- ^Klabukov, I.D.; Baranovskii, D.S. (2023). "The Engineering Biology Problems Book: Bridging the gap between biomedicine and engineering". Biomedical Research and Therapy. 10 (8): 5801–5803. doi:10.15419/bmrat.v10i8.821. ISSN 2198-4093.
Bibliography
- H.R.4521 - America COMPETES Act of 2022
https://www.congress.gov/congressional-record/2022/03/17/senate-section/article/S1237-5
- Schuergers, N., Werlang, C., Ajo-Franklin, C., & Boghossian, A. (2017). A Synthetic Biology Approach to Engineering Living Photovoltaics. Energy & Environmental Science. doi:10.1039/C7EE00282C
- Teague, B. P., Guye, P., & Weiss, R. (2016). Synthetic Morphogenesis. Cold Spring Harbor Perspectives in Biology, 8(9), a023929. doi:10.1101/cshperspect.a023929
- Kelley, N. J. (2015). Engineering Biology for Science & Industry : Accelerating Progress. http://nancyjkelley.com/wp-content/uploads/Meeting-Summary.Final_.6.9.15-Formatted.pdf
- HR591 – Gesetz zur Förderung der Forschung und Entwicklung in der Ingenieurbiologie von 2015. https://www.congress.gov/bill/114th-congress/house-bill/591
- Kelley, NJ (2014). Die Chancen und Herausforderungen der technischen Biologie in den Vereinigten Staaten. Industrial Biotechnology , 10(3), 137–139. doi:10.1089/ind.2014.1516
- ↑ Beal, J., Weiss, R., Densmore, D., Adler, A., Babb, J., Bhatia, S., ... & Loyall, J. (Juni 2011). TASBE: Eine Werkzeugkette zur Beschleunigung des synthetischen Bioengineerings. In: Proceedings of the 3rd International Workshop on Bio-Design Automation (S. 19–21). http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.467.7189&rep=rep1&type=pdf
- Schrödinger, E. (1946). Was ist Leben?: Der physikalische Aspekt der lebenden Zelle. Cambridge.
- Aufgabenbuch zur Ingenieurbiologie . 2016. doi:10.2139/ssrn.2898429
